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Line graph of the <t>diffraction</t> data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.
Diffraction Data, supplied by Oxford Cryosystems Ltd, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Line graph of the <t>diffraction</t> data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.
X Ray Diffraction Data, supplied by Oxford Cryosystems Ltd, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Line graph of the <t>diffraction</t> data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.
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Line graph of the <t>diffraction</t> data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.
Crystal Mounting And X Ray Diffraction Data Collection Supplies, supplied by Mitegen Llc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Line graph of the <t>diffraction</t> data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.
X Ray Diffraction Data, supplied by Rigaku Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Line graph of the <t>diffraction</t> data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.
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Line graph of the <t>diffraction</t> data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.
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Line graph of the <t>diffraction</t> data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.
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Line graph of the diffraction data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.

Journal: Acta Crystallographica Section D: Structural Biology

Article Title: Towards patient-relevant structures: reviewing body-temperature biological macromolecules and their ligands for pharmaceutical applications

doi: 10.1107/S2059798325010617

Figure Lengend Snippet: Line graph of the diffraction data-collection temperature (orange) of PDB structures that were determined at 310 K ( i.e. 37°C) and greater, together with the respective crystallization temperature (blue). Data from relevant crystallization studies are also included. Metadata details are available in Supplementary Tables S1 and S2.

Article Snippet: During the collection of diffraction data the temperature has so far been controlled via the CryoStream apparatus from Oxford Cryosystems ( https://oxcryo.com/products/cryostream/ ), which has a built-in heater device that achieves a range of crystal sample temperatures from 100 to 350 K. This device is very widely available, including at home X-ray laboratories, synchrotron beamlines and neutron macromolecular crystallography instruments.

Techniques: Crystallization Assay